Authors - Fawzy Alsharif, Irem Yildirim Abstract - Microwave imaging is a promising non-invasive technique for early stage cancer detection, leveraging its sensitivity to variations in the dielectric properties of biological tissues. In this work, a compact ultra-wideband (UWB) antenna specifically designed for lung cancer imaging is presented and analyzed through electromagnetic simulations. The antenna is fabricated on a Rogers RT5880 substrate (εr = 2.2, thickness = 1.65 mm) with overall dimensions of 23 × 21 × 1.58 mm³ and is impedance-matched to a 50 Ω feedline. Performance evaluations using CST and HFSS reveal operation across three frequency bands centered at 3.08 GHz, 6.04 GHz, and 9.54 GHz. The antenna achieves a peak gain of 4.52 dBi and a maximum radiation efficiency of 86% at the highest frequency. It offers a wide operational bandwidth from 2.58 GHz to 11.67 GHz. A realistic lung phantom modeled in CST demonstrates the antenna’s effectiveness in detecting signal changes caused by dielectric contrast in tissues, highlighting its potential for accurate and non-invasive lung cancer diagnosis.