Authors - Shreya Joshi, Vijay Ukani, Priyank Thakkar, Mrudangi Thakker, Dhruvang Thakker Abstract - This study introduces a hybrid malware detection approach that combines machine learning (ML) and deep learning (DL) techniques to enhance detection accuracy. By applying models like K-Nearest Neighbors (KNN), Support Vector Machine (SVM), and Gradient Boosting, we achieved 99.47% accuracy during training and 99.21% accuracy during testing, focusing on analyzing Portable Executable (PE) header data. Additionally, incorporating Convolutional Neural Networks (CNN) with Long Short-Term Memory (LSTM) networks improved performance, achieving 99% accuracy, 97% precision, and 98% recall after 30 epochs. The proposed hybrid method reduces false positives and negatives while demonstrating scalability across various datasets, offering a reliable and efficient solution for contemporary malware detection.